Some drugs can alter the production of saliva, causing dry mouth and increasing the occurrence of caries, stomatitis or glossitis, as is the case with tricyclic antidepressants that cause a metallic or bitter taste.
Other drugs, after ingestion, can be secreted in the saliva, causing a bitter taste, as is the case of antibiotics such as clarithromycin and tetracycline, which can result in excessive growth of fungi causing, for example, candidiasis.
Cisplatin or methotrexate are examples of drugs that cause stomatitis, glossitis and esophagitis that are expected effects of these antineoplastic agents.
These effects are normal consequences of the consumption of the drugs in question and they pass, in general, as soon as their ingestion is suspended.
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