Tranexamic acid is a substance that inhibits the action of an enzyme known as plasminogen, which normally binds to clots to destroy them and prevent them from forming a thrombosis, for example. However, in people with diseases that make blood very thin, plasminogen may also prevent the formation of clots during cuts, for example, making it difficult to staunch bleeding.
In addition, this substance also appears to prevent the normal production of melanin and therefore can be used to lighten some skin blemishes, especially in the case of melasma.
Due to its double action, this substance can be found in the form of tablets, to prevent bleeding, or in the form of cream, to help lighten blemishes. It can also be used as an injection in the hospital to correct emergencies related to excessive bleeding.
Price
The price of tranexamic acid can range from 30 to 60 reais for tablets depending on the business name and place to buy. The most commonly used trade names are Transamin or Trexacont.
In the form of cream, the average value is 40 reais, to about 30 grams.
What is it for
This substance is indicated for:
- Reduce the risk of bleeding during surgeries;
- Lighten melasmas and dark spots on the skin;
- Treat hemorrhages associated with excessive fibrinolysis.
The use of this substance in the form of tablets to treat or prevent the onset of bleeding should only be done after the advice of a doctor.
How to use
The dose and time of use of this medicine should always be directed by the doctor, however the general indications are:
- Treat or avoid bleeding in children : take 10 to 25 mg / kg, two to three times a day;
- Treat or prevent bleeding in adults : 1 to 1.5 grams, two to four times a day, for about 3 days. Or 15 to 25 mg / day if the treatment lasts more than 3 days;
- Lighten blemishes on the skin : Use a cream with a concentration between 0.4% to 4% and pass in the place to lighten. Apply sunscreen during the day.
The dose of the tablets may be adequate by the physician according to the patient's history, use of other medicaments and the effects shown.
Possible side effects
The most common side effects include nausea, vomiting, diarrhea, and a decreased blood pressure.
Who should not use
Tranexamic acid should not be used in people with hemophilia to be treated with another medicine, in patients with intravascular coagulation or with blood in the urine. In addition, it should also be avoided for chest or abdominal surgeries because there is a greater risk of bruising.