Otezia is a remedy that contains apremilast, a substance that blocks the action of an enzyme, called phosphodiesterase 4, which produces molecules of the immune system involved in the processes of inflammation that cause psoriasis and psoriatic arthritis, which alleviates the symptoms of these diseases .
This medicine can be bought in conventional pharmacies with a prescription, in the form of tablets containing 10, 20 or 30 mg of apremilast.
What is it for
Otezia is indicated for the treatment of moderate to severe plaque psoriasis and active psoriatic arthritis, which did not respond to treatment with other types of medications.
How to take
The recommended dose is 30 mg twice a day in the morning and at night with a 12-hour interval without having to eat.
However, to start using this medication, the following schedule should be followed:
| Morning | Evening | |
| Day 1 | 10 mg | --- |
| Day 2 | 10 mg | 10 mg |
| Day 3 | 10 mg | 20 mg |
| Day 4 | 20 mg | 20 mg |
| Day 5 | 20 mg | 30 mg |
| Day 6 and following | 30 mg | 30 mg |
In case of forgetting a dose it is recommended to take the next dose as soon as possible. If the next dose is next, you should wait for the usual time.
Main side effects
Some of the most common side effects include diarrhea, nausea, and headache, especially during the first 4 weeks after starting treatment.
Who should not take
Otezia should not be used by pregnant women, women who are breast-feeding, and people who are allergic to apremilast or any of the other ingredients of the formula.
