Anagrelide

Anagrelide is an antiplatelet medicine known commercially as Agrylin.

This oral medication has a mechanism of action not well understood, but its efficacy is guaranteed in the treatment of Thrombocythemia.

Indications of Anagrelide

Thrombocythemia (treatment).

Price of Anagrelide

The 0.5 mg Anagrelide vial containing 100 tablets costs approximately 2, 300 reais.

Side Effects of Anagrelide

Palpitation; increased heart rate; chest pain; Headache; dizziness; swelling; chills; fever; weakness; lack of appetite; abnormal burning sensation; tingling or touch-prone; nausea; abdominal pain; diarrhea; gases; vomiting; indigestion; eruption; itching.

Contraindications of Anagrelide

Pregnancy Risk C; women in the lactation phase; patients with severe hepatic impairment; Hipersensibility to any of the formula's components.

How to use Anagrelide

Oral use

Adults

• Thrombocythemia: Start treatment with 0.5 mg four times a day, or 1 mg twice daily. The treatment should last for 1 week.

Maintenance: 1.5 to 3 mg per day (adjust for lower effective dose).

Children and Adolescents from 7 to 14 years old

• Start at 0.5 mg per day for one week. The maintenance dose should be between 1.5 and 3 mg per day (adjust for the lowest effective dose).

Recommended maximum dose: 10 mg per day or 2.5 mg as single dose.

Patients with moderate hepatic impairment

• Reduce initial dose to 0.5 mg per day for at least one week. Increase the dose gradually respecting increments of at most 0.5 mg per day every week.