Pegaptanib is an anti-angiogenic drug that prevents the formation of new blood vessels, decreases vascular permeability and inflammation, and is used to treat the wet form of macular degeneration.
The wet form of vascular degeneration is a disease leading to loss of vision resulting from the injury to the central part of the retina, called the macula, at the back of the eye. The macula gives the eye the ability to provide a clear, central view that is needed for activities such as driving vehicles, reading high definition prints and other similar tasks.
Pegaptanib is the active ingredient in Macugen, produced by Pfizer.
Indications of Pegaptanib (Macugen)
Macugen is indicated for the treatment of age-related macular degeneration.
Price for Pegaptanib (Macugen)
The price of Macugen is approximately 3, 300 reais.
How to use Pegaptanib (Macugen)
The mode of use of Macugen consists of 0.3 mg injection, given once every 6 weeks, 9 times a year, by intravitreal injection into the chosen eye.
Treatment with Macugen should be administered only by intravitreal injection by ophthalmologists experienced in this type of administration.
Side effects of Pegaptanib (Macugen)
The side effects of Macugen may include eye inflammation, eye pain, increased pressure inside the eye, small marks on the surface of the eye, small particles or spots on vision, cataracts, conjunctival haemorrhage, conjunctival hyperemia, conjunctival edema, conjunctivitis, dystrophy cornea, corneal epithelial disorder, affection of the corneal epithelium, dry eye, increased lacrimation, macular degeneration, ocular discomfort, ocular hypertension, ear and labyrinth disorders, deafness, worsening Meniere's disease and vertigo.
Contraindications of Pegaptanib (Macugen)
Macugen is contraindicated in patients with eye infection in or around the eye or hypersensitivity to the active substance or to any of the components of the formulation.
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