Ambisome is an antifungal and antiprotozoal medicine with active substance Amphotericin B.
This injectable drug is indicated for the treatment of aspergillosis, visceral leishmaniasis and meningitis in patients with HIV, its action is to alter the permeability of the cell membrane of the fungus, which ends up being eliminated from the organism.
Ambisome Indications
Fungal infection in patients with febrile neuropathy; aspergillosis; cryptococcosis or disseminated candidiasis; visceral leishmaniasis; cryptococcal meningitis in patients with HIV.
Ambisome side effects
Chest pain; increased heart rate; Low pressure; high pressure; swelling; redness; itching; skin rash; sweating; nausea; vomiting; diarrhea; abdominal pain; blood in the urine; anemia; increased blood glucose; decreased calcium and potassium in the blood; back pain; cough; difficulty breathing; disorders of the lungs; rhinitis; nasal bleeding; anxiety; confusion; Headache; fever; insomnia; chills.
Contraindications of Ambisome
Pregnancy risk B; women in the lactation phase; hypersensitivity any component of the formula.
How to use Ambisome (Dosage)
Injectable Use
Adults and children
- Fungal infection in patients with febrile neuropathy: 3 mg / kg body weight per day.
- Aspergillosis; disseminated candidiasis; cryptococcosis : 3.5 mg / kg body weight per day.
- Meningitis in HIV patients : 6 mg / kg body weight per day.