Afatinib is a substance capable of blocking the action of a set of proteins, known as the ErbB family, that help tumor cells multiply. In this way, by using this substance it is possible to reduce the growth rate of non-small cell lung cancer.
This substance can be purchased in conventional pharmacies under the trade name Giotrif in 20, 30, 40 or 50 mg tablets.
Price
The price of this medicine can vary between 4, 500 and 6, 000 reais, depending on the dosage of the tablets.
What is it for
Afatinib is indicated for the treatment of locally advanced or metastatic non-small cell lung cancer without prior exposure to TKI of the epidermal growth receptor or with squamous histology that worsened during or after chemotherapy.
How to take
The recommended dose is 40 mg per day, ingested as fast as 1 hour before eating breakfast.
However, the dose needs to be adequate according to the severity of the disease and the response to the drug, with the physician's guidance being very important.
Main side effects
Use of this medication may cause some side effects such as decreased appetite, dehydration, urinary tract infection, nosebleeds, coryza, eye infection, dry eyes, hives on the skin, fever, weight loss, and dry skin.
Who should not take
Afatinib is contraindicated for pregnant women, breast-feeding women, and people with an allergy to afatinib or any other component of the formula. In addition, in patients with heart, liver or lung problems should only be used with advice from a physician.
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