Protamine

Protamine is an injectable drug used to neutralize the anticoagulant action of heparin in adults.

Protamine should be given through the vein by a health care professional.

Indications of Protamine

Protamine is indicated to neutralize the anticoagulant action of heparin in cases of severe hemorrhage related to the use of heparin and to neutralize the effect of heparin administered preoperatively and during extracorporeal circulation, such as in dialysis and cardiac surgeries.

How to use Protamine

The mode of use of Protamine should be guided by the physician according to the objective.

Side Effects of Protamine

Protamine side effects include decreased blood pressure, decreased heart rate, feeling hot, shortness of breath, nausea, vomiting, tiredness, allergy, bleeding, back pain, respiratory failure, circulatory collapse, stroke, and acute pulmonary hypertension .

Contraindications of Protamine

Protamine is contraindicated in patients with hypersensitivity to the components of the formula.

In addition, this medicinal product should not be used by pregnant women without medical advice.

See too:

• Heparin (Liquemine)