Kadcyla is a medicine indicated for the treatment of breast cancer already with several metathetics in the body. This medicine works by preventing the growth and formation of new cancer cell metastases.
Kadcyla is a drug produced by the pharmaceutical company Roche.
Indications of Kadcyla
Kadcyla is indicated for the treatment of breast cancer already at an advanced stage and already spread to other parts of the body. It is usually given to the patient after other cancer drugs are given and there has been no success.
The drug Kadcyla consists of two drugs, trastuzumab that prevents the growth of cancer cells and the mertansine that enters the cells and destroys them, reducing the tumor and progress of the disease, as well as prolong the life of the patient.
Price of Kadcyla
The price of Kadcyla per month is $ 9800, and a treatment course of 9.6 months will cost $ 94, 000.
How to use Kadcyla
The recommended dose of Kadcyla is 3.6 mg / kg and is given by intravenous injection every 3 weeks.
In the first treatment the drug should be administered for 90 minutes, and patients should be observed to check for side effects. If it is well tolerated, the medicine should be given for at least 30 minutes.
Doses above 3.6 mg / kg should not be administered.
Side effects of Kadcyla
The side effects of Kadcyla are:
- Fatigue;
- Nausea and vomiting:
- Muscle pain;
- Reduction in the number of platelets in the blood;
- Headache;
- Increased liver transaminases;
- Constipation.
Contraindications of Kadcyla
Kadcyla is contraindicated during pregnancy because it causes serious genetic and life-threatening problems for the baby.
Some medicines may interact with Kadcyla as
- Imatinib;
- Isoniazid;
- Clarithromycin and telithromycin;
- Antifungal medicines;
- Medications for the heart: nicardipine, quinidine;
- Medicines for hepatitis C: boceprevir, telaprevir;
- AIDS drugs;
- Vitamins and natural products.
The doctor should always be informed of the medicines the patient regularly or is taking at the time of starting treatment.