Estradiol is one of the active ingredients of a recommended anti-menopause discomfort drug, sold commercially under the name Prefest.
Indications
Menopause, vulvovaginal atrophy, prevention of osteoporosis.
Contraindications
Pregnancy, breast tumor, bleeding, thrombophlebitis.
Adverse effects
Pain in the breast, vaginal bleeding, dysmenorrhea, vaginitis, depression, insomnia, migraine, fatigue, uterine polyp, overweight, edema, anemia.
How to use
From day 1 to day 3: 1 estradiol tablet.
From day 4 to day 6: 1 estradiol tablet + 1 estradiol tablet with norgestimate. And so on, according to the markings made on the carton of the medicine.
Useful link:
Estradiol (Climaderm)