Anagrelide is an antiplatelet drug known commercially as Agrylin.
This medication for oral use has a mechanism of action that is not well understood, but its effectiveness is guaranteed in the treatment of thrombocythemia.
Indications for Anagrelide
Thrombocythaemia (treatment).
Anagrelida Price
The 0.5 mg bottle of Anagrelide containing 100 tablets costs approximately 2,300 reais.
Side Effects of Anagrelide
Palpitation; increased heart rate; chest pain; headache; dizziness; swelling; chills; fever; weakness; lack of appetite; abnormal burning sensation; tingling or prickling to the touch; nausea; abdominal pain; diarrhea; gases; vomiting; indigestion; eruption; itch.
Contraindications for Anagrelide
Pregnancy Risk C; lactating women; patients with severe liver failure; Hipersensibility to any of the formula's components.
Directions for use of Anagrelide
Oral use
Adults
- Thrombocythaemia: Start treatment with 0.5 mg four times a day or 1 mg twice a day. Treatment should last for 1 week.
Maintenance: 1.5 to 3 mg per day (adjust to lowest effective dose).
Children and Adolescents from 7 to 14 years old
- Start with 0.5 mg daily for a week. The maintenance dose should be between 1.5 to 3 mg per day (adjust to the lowest effective dose).
Maximum recommended dose: 10 mg daily or 2.5 mg as a single dose.
Patients with moderate hepatic impairment
- Reduce starting dose to 0.5 mg daily for at least a week. Increase the dose gradually respecting increments of a maximum of 0.5 mg per day each week.
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