Anforincin B is an antifungal medicine active against amphotericin B.
This injectable drug is indicated for the treatment of leishmaniasis, aspergillosis and blastomycosis, since its action alters the permeability of the cell wall of the fungus, reducing the symptoms of the infection.
Indications of Anforicin B (For what it is)
Cutaneous-mucosal leishmaniasis; cryptococcal meningitis; aspergillosis; blastomycosis; disseminated candidiasis; coccydiomycosis; cryptococcosis; fungus endocartitis; histoplasmosis; mucormycosis; disseminated sporotrichosis; septicemia by fungi; urinary tract infection.
Side effects of Anforicin B
Inflammation in the vein; Low pressure; increased respiratory movements; rash; pain at the injection site; abnormal kidney function; decreased urine density; renal tubular acidosis; kidney stone; lack of appetite; nausea; vomiting; indigestion; diarrhea; stomach ache; colic; heartburn; anemia; weight loss; decreased potassium in the blood; Headache; fever; chills; malaise
Contraindications of Anforicin B
Pregnancy risk B; women in the lactation phase; Hipersensibility to any of the formula's components.
How to use Anforicin B (Dosage)
Injectable Use
Adults and adolescents
- Start with administration of 0.25 to 0.3 mg / kg of body weight per day for 2 to 6 hours. Doses can be gradually increased by 5 to 10 mg per day up to the maximum daily dose of 1 mg / kg of weight.
Children
- Candidiasis: 0.5 to 1 mg / kg of body weight per day in 5% Glucose for 6 hours.