Daraprim is an antimalarial drug that uses pyrimethamine as an active ingredient and is capable of inhibiting the production of enzymes by the protozoan responsible for malaria, thus treating the disease.
Daraprim can be purchased from conventional prescription drug stores in the form of cartons with 100 25-mg tablets.
Price
The price of Daraprim is approximately 7 reais, however the amount may vary according to the place where the medication is purchased.
Indications
Daraprim is indicated for the prevention and treatment of malaria along with other medicines. In addition, Daraprim may also be used to treat Toxoplasmosis, as directed by your doctor.
How to use
The mode of use of Daraprim varies according to the purpose of treatment and the age of the patient, and the general guidelines include:
Prevention of malaria
- Adults and children over 10 years: 1 tablet per week;
- Children between the ages of 5 and 10: ½ tablet per week;
- Children under 5 years: ¼ tablet per week.
Treatment of malaria
- Adults and children over 14 years: 2 to 3 tablets together with 1000 mg to 1500 mg of single dose sulfadiazine;
- Children aged 9 to 14 years: 2 tablets together with 1000 mg of single dose sulfadiazine;
- Children aged 4 to 8 years: 1 tablet together with 1000 mg of single dose sulfadiazine;
- Children under 4 years: ½ tablet together with 1000 mg of sulfadiazine in a single dose.
Side effects
The main side effects of Daraprim include skin allergy, palpitations, nausea, cramps, diarrhea, lack of appetite, blood in the urine and changes in blood test.
Contraindications
Daraprim is contraindicated in patients with secondary megaloblastic anemia due to folate deficiency or with hypersensitivity to pyrimethamine or any of the components of the formula.
