Myalept is a medicine that contains an artificial form of leptin, a hormone produced by fat cells that acts on the nervous system regulating the sensation of hunger and metabolism and is therefore used to treat the consequences in patients with low fat, as in the case of congenital lipodystrophy, for example.
Myalept contains in its composition metreleptin and can be purchased in the United States with a prescription, in the form of a subcutaneous injection, similar to insulin pens.
Myalept Indications
Myalept is indicated as a replacement therapy in patients with leptin-related complications, as in the case of generalized acquired or congenital lipodystrophy.
How to use Myalept
The mode of use of Myalept varies according to the patient's weight and gender, and the general guidelines include:
- Body weight of 40 kg or less: initial dose of 0.06 mg / kg / day, and may be increased up to a maximum of 0.13 mg / kg / day;
- Men over 40 kg: initial dose of 2.5 mg / kg / day, and may be increased up to a maximum of 10 mg / kg / day;
- Women over 40 kg: initial dose of 5 mg / kg / day, and may be increased up to a maximum of 10 mg / kg / day.
Therefore, the dose of Myalept should always be indicated by an endocrinologist. Myalept is given with a shot under the skin, so it is important to get advice from a doctor or nurse about how to use the injection.
Side Effects of Myalept
The major side effects of Myalept include headaches, weight loss, abdominal pain and reduced blood sugar levels, which can cause easy tiredness, dizziness and cold sweats.
Contraindications of Myalept
Myalept is contraindicated for patients with obesity not associated with congenital leptin deficiency or with hypersensitivity to metreleptin.
Here's how treatment for these types and diseases should be:
- How to treat generalized congenital lipodystrophy
