Some drugs can alter the production of saliva, causing dry mouth and increasing the occurrence of cavities, stomatitis or glossitis, as in the case of tricyclic antidepressants that provoke a metallic or bitter taste.
Other drugs, after ingestion, can be secreted into the saliva, causing bitter taste, such as antibiotics such as clarithromycin and tetracycline, which may result in excessive fungal growth causing, for example, candidiasis.
Cisplatin or metotexane are examples of drugs that cause stomatitis, glossitis and esophagitis, which are expected effects of these antineoplastics.
These effects are normal consequences of the consumption of the medicines in question and generally pass as soon as their ingestion is suspended.