PFAPA syndrome is a rare genetic disease that develops in infancy up to five years of age. In this syndrome the child develops monthly symptoms such as fever, aphthous stomatitis or pharyngitis and adenitis.
This disease is benign and the children who suffer from it go through periods of fevers that last from three to five days with intervals of 28 days. Between one period and another of fever the child is healthy developing normally. Symptoms diminish with advancing age and child carriers do not have long-term sequelae.
Treatment is done with the drug prednisone to improve symptoms.
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