Propafenone

Propafenone is the active substance in an antiarrhythmic medication known commercially as Ritmonorm.

This medication for oral and injectable use is indicated for the treatment of cardiac arrhythmias, its action decreases the excitability, the speed of conduction of the heart, keeping the heartbeat stable.

Propafenone Indications

Ventricular arrhythmia; supraventricular arrhythmia.

Propafenone Price

The box of 300 mg of Propafenone containing 20 tablets costs approximately 54 reais and the box of 300 mg medicine containing 30 tablets costs approximately 81 reais.

Side Effects of Propafenone

Vomiting; nausea; dizziness; lupus-like syndrome; swelling; angioneurotic.

Contraindications for Propafenone

Pregnancy Risk C; breast-feeding; asthma or non-allergic bronchospasm such as emphysema or chronic bronchitis (may worsen); atrioventricular block; sinus bradycardia; cardiogenic shock or severe hypotension (may worsen); uncontrolled congestive heart failure (may worsen); sinus node syndrome; electrolyte balance disorders (pro-arrhythmic effects of propafenone can be enhanced); pre-existing disorders in cardiac conduction (atrio-ventricular, intraventricular and syncatrial) in patients who do not use a pacemaker.

How to use Propafenone

Oral use

Adults weighing more than 70 kg

• Start with 150 mg every 8 hours; if necessary, increase (3 to 4 days after) to 300 mg, twice a day (every 12 hours).

Dose limit for adults: 900 mg per day.

Patients weighing less than 70 kg

• They should have their daily doses reduced.

Elderly or Patients with severe cardiac damage

• They should receive the product in increasing doses, during the initial adjustment phase.

Injectable Use

Adults

• Urgent application: 1 to 2 mg per kg of body weight, by direct intravenous route, administered slowly (from 3 to 5 minutes). Use a 2nd dose only after 90 to 120 minutes (by intravenous infusion, for 1 to 3 hours).

Maintenance: 560 mg in 24 hours (70 mg every 3 hours); the acute condition has ceased: use profenanone tablet (300 mg every 12 hours).

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