Vincristine

Vincristine is the active substance of an antineoplastic medicine known commercially as Oncovin.

This injectable drug is used to treat individuals with different cancers including leukemia, lung and breast cancer. Its action consists in interfering in the metabolism of the amino acids and to prevent the cellular division, diminishing the probability of the cancer to spread by the organism.

Vincristine Indications

Leukemia; neuroblastoma; Wilms' tumor; Breast cancer; lung cancer; Ovary cancer; cervical cancer; colorectal cancer; Hodgkin's lymphoma; Ewing's sarcoma; osteorssacoma; malignant melanoma; mycosis fungoides; ovarian tumor.

Vincristina price

The box of 1mg of Vincristina costs approximately 40 reais.

Side Effects of Vincristine

Hair loss.

Contraindications of Vincristine

Pregnancy risk D; women in the lactation phase; Severe bacterial infection; Charcot-Marie-Tooth syndrome; bowel obstruction.

How to use Vincristine

Injectable Use

Adults

• Administer 0.01 to 0.03 mg Vincristine per kg body weight as a single dose. The procedure should be done every 7 days.

Children

• Above 10 kg: Administer 1.5 to 2 mg of Vincristine square meter body surface, as a single dose. The procedure should be done every 7 days.
• At 10 kg or less: Give 0.05 mg Vincristine per kg body weight as a single dose. The procedure should be done every 7 days.